J2405 - Ondansetron injection - medication given by injection to prevent nausea and vomiting

Healthcare Common Procedure Coding System

Last updated: 11/28/2025

What is a HCPCS Code?

HCPCS (Healthcare Common Procedure Coding System) codes are used to identify medical procedures, supplies, and services for billing purposes. These codes help standardize how healthcare services are reported and billed across different providers and insurance companies.

Detailed Description

This code represents an injection of ondansetron hydrochloride, a medication commonly used to prevent or treat nausea and vomiting. The code covers the cost per 1 milligram of the medication when given by injection (into a vein, muscle, or under the skin). Ondansetron works by blocking certain signals in the body that trigger nausea and vomiting. This injectable form is typically used when oral medications cannot be taken or when faster relief is needed.

Additional Information

Dosing is calculated per milligram, so total cost depends on the prescribed dose. This medication is generally well-tolerated with few side effects. The injectable form provides faster onset compared to oral forms.

Category

Injectable Medications

Medical Specialty

Multiple specialties (oncology, surgery, emergency medicine, gastroenterology)

Expected Costs

Your actual cost will depend on your insurance coverage, provider location, and specific circumstances.

What's Required Before This

  • Medical evaluation to determine need for anti-nausea medication
  • Assessment of patient's ability to receive injections

What to Expect After

  • Monitor for effectiveness in controlling nausea/vomiting
  • Watch for any adverse reactions
  • Assess need for additional doses

Why Understanding This Code Matters

On Your Medical Bill

This code appears on your medical bills to identify the specific service, procedure, drug, or medical diagnosis you received. Understanding what it means helps you verify you're being charged correctly and know what to expect.

For Your Health

Knowing what this code represents helps you understand your treatment plan, ask better questions during appointments, and track your healthcare journey more effectively.

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